Flares observed with XMM-Newton and the VLA

We present lightcurves obtained in X-ray by the XMM-Newton EPIC cameras and simultaneous radio lightcurves obtained with the VLA for five active M-type flare stars. A number of flare events were observed, and by comparing radio with X-ray data, we consider various possible flare mechanisms. In cases where there seems to be a clear correlation between radio and X-ray activity, we use an energy budget argument to show that the heating which leads to the X-ray emission could be due to the same particles emitting in the radio. In cases where there is radio activity without corresponding X-ray activity, we argue that the radio emission is likely to arise from coherent processes involving comparatively few particles. In one case, we are able to show from polarization of the radio emission that this is almost certainly the case. Cases for which X-ray activity is seen without corresponding radio activity are more difficult to explain. We suggest that the heating particles may be accelerated to very high energy, and the resulting synchrotron radio emission may be beamed in directions other than the line of sight.Comment: 12 pages, 10 figure

Adherence to prophylaxis in adolescents and young adults with severe haemophilia, A qualitative study with patients

© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.Abstract Introduction: Reported levels of adherence to prophylaxis among young people with haemophilia (YPH) vary widely and are predominately based on estimations made by healthcare professionals and parents. Reasons for (non)adherence among YPH in particular have not been evidenced. Aim: to examine experiences in relation to prophylaxis with YPH themselves, and barriers and facilitators to their adherence. Methods: 11 Participants were recruited in five haemophilia centres across England and Wales. All patients who met the inclusion criteria (aged 12-25, diagnosed with haemophilia, on prophylaxis) were approached during a routine check-up appointment, and all participants who agreed to take part were interviewed. Interviews were audio recorded, transcribed and analysed using Interpretative Phenomenological Analysis. Results: Self-reported adherence to prophylaxis was good. Few participants admitted to intentionally skipping injections although they reported sometimes forgetting. However, due to the increasingly personalised and flexible approach to prophylaxis, adherence is not straightforward to define. Barriers to adherence included a busy lifestyle, dislike of the intravenous injection, venous access issues, anxiety or stress and being out of one’s normal routine. Support was an important facilitator to adherence, including support from health professionals at the haemophilia centre as well as friends. Parents appear to be very involved with their sons’ haemophilia management, even after their sons leave home. Conclusion: What this study adds is that the increasingly flexible and personalized approach to managing prophylaxis in haemophilia may sometimes lead to confusion around treatment frequency and dosing. This may lead to accidental non-adherence, which is distinct from both skipping and forgetting. Advice from haemophilia teams may not always be consistent, and is likely to be interpreted differently by different individuals. Some additional training and education of patients and their families to increase their knowledge and skills around prophylaxis may reduce this confusion and therefore is likely to improve adherence further.Peer reviewedFinal Published versio

Reactivation of contraction in detergent-lysed teleost retinal cones.

Teleost retinal cones contract in the light and elongate in the dark. In the green sunfish, Lepomis cyanellus, the necklike myoid region of the cone contracts from as much as 120 micrometers (midnight dark-adapted) to 6 micrometers in fully light-adapted state. When dark-adapted fish are exposed to light (1.4 lux), cone myoids contract with a linear rate of 1.5 +/- 0.1 micrometers/min. We report here that detergent-lysed motile models of teleost retinal cones exhibit calcium- and ATP-dependent reactivated contraction, with morphology and rate comparable to that observed in vivo. For reactivation studies isolated dark-adapted retinas were lysed with nonionic detergent Brij-58 (0.1-1.0%). In reactivation medium containing 10(-5) M free calcium and 4 mM ATP, the lysed cones contracted with normal morphology at in vivo rates (1.4 +/- 1 micrometer/min). Little contraction was observed if ATP or detergent was deleted from the medium or if free calcium levels were less than 10(-8) M. Ultrastructural examination of cone models lysed with 1% Brij-58 revealed that, in spite of extensive extraction of the cytoplasmic matrix, cytoskeletal components (thin filaments, intermediate filaments, microtubules) were still present. Thus we have produced extensively extracted motile models of teleost retinal cones which undergo calcium- and ATP-dependent reactivated contraction with normal morphology at physiological rate

X-ray Halos and Large Grains in the Diffuse Interstellar Medium

Recent observations with dust detectors on board the interplanetary spacecraft Ulysses and Galileo have recorded a substantial flux of large interstellar grains with radii between 0.25 and 2.0 mu entering the solar system from the local interstellar cloud. The most commonly used interstellar grain size distribution is characterized by a a^-3.5 power law in grain radii a, and extends to a maximum grain radius of 0.25 mu. The extension of the interstellar grain size distribution to such large radii will have a major effect on the median grain size, and on the amount of mass needed to be tied up in dust for a given visual optical depth. It is therefore important to investigate whether this population of larger dust particles prevails in the general interstellar medium, or if it is merely a local phenomenon. The presence of large interstellar grains can be mainly inferred from their effect on the intensity and radial profiles of scattering halos around X-ray sources. In this paper we examine the grain size distribution that gives rise to the X-ray halo around Nova Cygni 1992. The results of our study confirm the need to extend the interstellar grain size distribution in the direction of this source to and possibly beyond 2.0 mu. The model that gives the best fit to the halo data is characterized by: (1) a grain size distribution that follows an a^-3.5 power law up to 0.50 mu, followed by an a^-4.0 extension from 0.50 mu to 2.0 mu; and (2) silicate and graphite (carbon) dust-to-gas mass ratios of 0.0044 and 0.0022, respectively, consistent with solar abundances constraints. Additional observations of X-ray halos probing other spatial directions are badly needed to test the general validity of this result.Comment: 17 pages, incl. 1 figure, accepted for publ. by ApJ Letter

Solution scheme for time dependent hydrodynamic plasma flow along a magnetic field line

Mathematical model for solving hydrodynamic flow equations in nonhomogenous magnetic field for plasma flow along field line in presence of gravitational fiel

Red Crossbill Invasion of Northwestern Arkansas during 2012-2013

An irruption of Red Crossbills (Loxia curvirostra) occurred in primarily northwestern Arkansas starting in November of 2012 and lasting to the end of May of 2013. Based on recordings of call notes, most birds around Fayetteville were Type 2, the large-billed ponderosa pine crossbill, associated with a variety of conifer species. Birds recorded in Carroll County were Type 3, the small-billed western hemlock crossbill, and they were associated with small cones on shortleaf pine (Pinus echinata). One recording was obtained in Fayetteville of Type 5, the lodgepole pine crossbill, only the third recording east of the Great Plains. Crossbills at the Fayetteville Country Club were observed eating algae (Cladophora sp.) during the months of December and January, a behavior rarely reported for passerines. During March, crossbills appeared at sunflower bird feeders, which is a relatively recent phenomenon associated with low conifer seed abundance. The first two Arkansas specimens of crossbills (probably Type 3) were obtained from birds that struck windows near feeders. This is only the third recorded irruption of crossbills in Arkansas in the last 43 years, suggesting that crossbills rarely travel this far south in search of cone crops